Cannabis Dispensary Durham NC

Founded in 2017 by Mary Lopez Carter, Carolina Hemp Hut on Durham-Chapel Hill Boulevard claims more SKUs than any dispensary in NC and has won IndyWeek's Best of the Best in the Triangle (2023, 2025) and Best of Durham (2024). Same-day delivery available across the Durham and Chapel Hill area.

Emerald Medicine Company on North Pointe Drive takes an alternative medicine approach to hemp retail, presenting CBD and wellness products through a health-centered lens rather than a recreational one. The professional atmosphere and curated selection serve the North Durham and Duke University area.

Hempie's Durham on Glenn School Road brings the WRAL and IndyWeek award-winning brand to North Durham, open daily until 10pm with THCa, Delta-9, Delta-8, THCP, CBD, and lab-tested edibles. The family-owned chain started in 2021 and now operates eight locations across North Carolina.

Oak City Hemp on North Roxboro Street in North Durham carries third-party tested flower, edibles, and concentrates with DoorDash delivery for those who prefer to order from home. Extended Friday and Saturday hours until 10pm make it a solid after-work and evening option.

Redhead Hemp's downtown Durham location on East Chapel Hill Street offers one of the longer retail windows in the city, with evening hours and a product range covering premium CBD, Delta-8, Delta-9, THCa, inhalables, edibles, and the brand's house-made drinks. Steps from Durham's restaurant and entertainment district.

Sherlocks's Durham location on Broadway Street opened in 2019, bringing the same dual dispensary-and-glass-gallery concept downtown. Live glass blowing events every Wednesday are a signature draw, alongside THCa flower, edibles, vapes, and exclusively American-made artisan glass. Only THCa, Delta-9, and CBD — no Delta-8.

The Hemptender on NC-54 near Southpoint serves the growing Southwest Durham corridor with a one-stop selection of smokeables, edibles, glassware, vapes, and CBD products. The shop emphasizes breadth and helpfulness, making it approachable for first-time hemp buyers and experienced consumers alike.